나이가 들어감에 따라, 무언가를 떠올리려고 하는데 생각이 잘 나지 않고, 기억력이 떨어지는 것 같은 느낌을 받을 때가 있습니다. 치매의 전조 증상이 아닌지 걱정이 되기 시작합니다. 이번 포스팅에서는 흔히 뇌영양제라고 부르는 건강기능식품들에 대해 알아보도록 하겠습니다.
알파 GPC
가장 먼저, 살펴볼 성분은 알파 GPC(alpha-GPC) 입니다. 다른 말로는 콜린 알포세레이트라고도 하며, 미국에서는 처방전 없이도 살 수 있는 건강기능식품에 해당하지만 국내에서는 전문의약품으로 분류되어 있어 의사의 처방전이 있어야 살 수 있습니다. 어르신들 사이에서 흔히 뇌영양제, 치매예방약으로 알려진 바로 그 성분입니다. 국내 제약사에서 출시한 글리아티린, 글리아타민 등의 약이 이에 해당합니다. 우리나라에서는 전문의약품으로 분류되어 있기 때문에, 이번 포스팅에서 소개 드릴 영양제 중에서 가장 효과적인 면에서는 확실하다고 할 수 있겠습니다.
그렇다면, 알파 GPC은 어떤 작용기전을 통해 효과를 나타낼까요?
우리 뇌의 신경계에서는 아세틸콜린(Acetyl choline)이라는 물질이 신호 전달 과정에 관여하는데, 알파GPC는 아세틸콜린의 전구체로서 알파GPC를 섭취할 경우 아세틸콜린의 합성이 더 많아지게 되고 뇌의 신경계가 더 활성화됩니다.
우리나라에서는 전문의약품이기 때문에 한 때는 아이허브 등에서 판매하는 제품의 통관이 허용되지 않았으나, 해외에서는 슈퍼에서도 살 수 있는 제품이라는 불만이 많아 현재는 통관이 가능하게 되었습니다.
포스파티딜 세린
뇌영양제 포스파티딜 세린은 인지질 성분으로 뇌의 신경세포막의 주요한 구성 성분입니다. 미국 등 서구에서는 이전부터 연구가 많이 되어 FDA에서도 기능성을 인정받았으나, 국내에서는 최근 들어 각광받고 있는 성분입니다.
포스파티딜 세린은 생체막을 회복시키고, 수상돌기의 밀도를 증가시키며, 신경성장인자 (Nerve Growth Factor)의 생성을 높이는 작용기전을 통해 기억력, 집중력, 인지력 향상에 도움을 주는 것으로 알려져 있습니다.
또한, 매일 하루 300mg 이상 섭취한 경우에는 섭취하지 않은 군에 비해 기억력, 학습능력, 인지력, 숫자암기력 등이 상당히 향상되었다는 임상 시험 데이터도 보고되었습니다.
국내 식약처에서도 기능성원료로 인정하여, 국내에서도 건강기능식품으로 많은 제품들이 나와 있습니다.
뇌영양제 추천 제품
닥터스 베스트, AlphaSize 및 SerinAid 함유 천연 두뇌 영양제, 베지 캡슐 60정
아이허브에서 닥터스 베스트 제품이 위에서 설명 드린 알파 GPC과 포스파티딜 세린 복합제의 형태로 판매되고 있어, 조합이 좋은 것으로 생각됩니다. 2정 기준으로 알파GPC 300mg+포스파티딜세린 100mg이 포함되어 있습니다. 가격은 현재 27,000원대로 나와 있습니다. 제조사의 권장 용량은 하루 2알로 되어 있으나 뇌 기능개선제 제품의 경우 하루 권장량이 따로 정해진 바가 없기 때문에 본인에게 맞는 용량을 찾아가는게 중요 할 것 같습니다. 또한, 사람에 따라 불면증을 유발한다는 보고가 있기 때문에 적어도 오후4시 이전에 섭취하는 게 좋을 것 같습니다.
Now Foods (나우 푸드), 알파-GPC, 300mg, 베지 캡슐 60정
또한 알파 GPC 단일 성분으로 나우푸드 제품이 있습니다. 이 제품의 경우 1정에 300mg의 알파gpc가 포함되어 있으며, 가격은 현재 1통에 31,000원대입니다. 유명한 나우푸드 제품이기 때문에 원료 등에 있어서는 믿을만 하다고 생각합니다.
닥터스 베스트, SerinAid 함유 포스파티딜세린, 100mg, 베지 캡슐 120정
포스파티딜 세린 단일 성분으로서, 닥터스 베스트 1정 100 mg제품이 120정에 33,000원대에 판매되고 있습니다. 포스타티딜 세린의 경우 많은 연구에서 하루 300mg이상 섭취시 효과가 있었다는 보고가 있고, 국내제품들의 경우 300mg을 권장용량으로 하고 있기 때문에 3정을 섭취해야 유효한 효과를 낼 것으로 생각합니다.
지금까지 뇌 영양제인 알파GPC와 포스파티딜 세린에 대해 알아보았습니다. 그렇지만 뇌영양제의 효과에 대한 연구는 아직 미약하며, 이 성분들이 치매와 같은 질병을 예방하거나 치료하는 데 효과적이라는 것은 확실하지 않습니다. 따라서, 이러한 제품을 사용하기 전에는 의사나 약사와 상담하는 것이 좋습니다.
다음 포스팅에서는 다른 종류의 뇌기능 개선제에 대해 다루어 보도록 하겠습니다.
콜린 알포세레이트 직구가 가능한거였군요
그렇습니다. 저도 복용중인데 집중이 잘되는 것 같아요.
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